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How to Determine if You Have Gluten Intolerance

February 14, 2026
Struggling with bloating or fatigue? Learn how to determine if you have gluten intolerance and find clarity with our expert guide. Start your path to wellness now.

Table of Contents

  1. Introduction
  2. Understanding the "Gluten" Umbrella
  3. Common Signs and "Mystery" Symptoms
  4. The Smartblood Method: Step 1 – Consult Your GP
  5. The Smartblood Method: Step 2 – The Elimination Approach
  6. The Smartblood Method: Step 3 – Targeted IgG Testing
  7. Deciphering Your Results: Is It Just Gluten?
  8. Practical Steps for Living with Gluten Intolerance
  9. Why Choose Smartblood?
  10. Summary: Your Path to Clarity
  11. FAQ

Introduction

It is a scenario many people in the UK know all too well: you finish a sandwich at lunch or a hearty bowl of pasta for dinner, and within an hour, you feel as though you have swallowed a lead weight. Your stomach distends, your energy levels plummet, and a strange "fog" seems to descend over your thoughts. You might dismiss it as "just one of those things" or a busy week at work, but when these episodes become a regular feature of your life, the question inevitably arises: is it the gluten?

Determining if you have a gluten intolerance—often medically referred to as Non-Celiac Gluten Sensitivity (NCGS)—can feel like navigating a maze without a map. With so much conflicting information online and a sea of "gluten-free" products on every supermarket shelf from Tesco to Waitrose, it is difficult to know where to start. Are your symptoms a genuine reaction to the protein in wheat, or could they be related to something else entirely, such as IBS or even a more serious autoimmune condition?

At Smartblood, we believe that true well-being comes from understanding the body as a whole, rather than simply chasing isolated symptoms. We know how frustrating "mystery symptoms" can be, and we are here to help you find clarity. This article is designed for anyone struggling with persistent digestive discomfort, fatigue, or skin issues who suspects gluten might be the culprit.

We will explore the physiological differences between allergies, autoimmune diseases, and intolerances, and provide a clear, clinically responsible path forward. Our approach, the Smartblood Method, prioritises your safety and long-term health. We advocate for a phased journey: consulting your GP first to rule out underlying medical conditions, followed by structured elimination trials, and finally, using targeted testing as a tool to remove the guesswork.

Understanding the "Gluten" Umbrella

Before we can determine if you have an intolerance, we must first understand what gluten actually is. Gluten is not a single molecule but a group of proteins—principally gliadin and glutenin—found in grains such as wheat, barley, and rye. In the kitchen, gluten acts as the "glue" that gives bread its elasticity and cakes their structure.

While most people can digest these proteins without issue, for a significant minority, gluten triggers a range of physical reactions. However, not all reactions are created equal. To find the right solution, we must distinguish between three very different conditions: Coeliac disease, wheat allergy, and gluten intolerance.

Coeliac Disease: The Autoimmune Factor

Coeliac disease is an autoimmune condition, not an intolerance or an allergy. When someone with coeliac disease eats gluten, their immune system mistakenly attacks their own healthy tissues—specifically the lining of the small intestine. This causes damage to the villi (the tiny, finger-like projections that absorb nutrients), leading to malabsorption, anaemia, and other long-term health complications.

Wheat Allergy: The Immediate Reaction

A wheat allergy is a classic IgE-mediated allergy. This involves the immune system producing Immunoglobulin E (IgE) antibodies in response to wheat proteins. Unlike an intolerance, which is often delayed, an allergic reaction usually happens very quickly—from a few seconds to two hours after exposure.

Safety Note: If you experience swelling of the lips, face, or throat, difficulty breathing, wheezing, or a sudden drop in blood pressure after eating, you must seek urgent medical help immediately by calling 999 or attending A&E. These are signs of anaphylaxis, a life-threatening allergic reaction. Food intolerance testing is not suitable for diagnosing these acute, severe allergies.

Gluten Intolerance (Non-Celiac Gluten Sensitivity)

Gluten intolerance is more of a "grey area" in clinical terms. It is often characterised by delayed symptoms—sometimes appearing up to 48 hours after consumption—that do not involve the same autoimmune damage as coeliac disease or the immediate histamine response of an allergy. Instead, it often involves a different part of the immune system, specifically IgG (Immunoglobulin G) antibodies.

Understanding these distinctions is the first step in knowing how to determine if you have gluten intolerance without overlooking a more serious underlying issue.

Common Signs and "Mystery" Symptoms

One of the reasons it is so difficult to pinpoint a gluten intolerance is that the symptoms are often non-specific. They "mimic" other conditions, leading many people to spend years suffering in silence or receiving an umbrella diagnosis like Irritable Bowel Syndrome (IBS).

If you are trying to decide if gluten is your problem, look for these common clusters:

1. Digestive Distress

This is the most common sign. It typically manifests as bloating and abdominal pain. You might find that your stomach feels "stretched" or uncomfortable shortly after a meal containing bread, pasta, or biscuits. Diarrhoea or constipation (or a frustrating mix of both) are also hallmark signs of a sensitive gut.

2. The "Brain Fog" Phenomenon

Many of our clients at Smartblood report a strange mental sluggishness. This "brain fog" makes it difficult to concentrate, find words, or stay focused on tasks. While it sounds vague, it is a very real symptom for those whose bodies are struggling with an inflammatory response to specific foods.

3. Chronic Fatigue

If you are sleeping eight hours a night but still waking up feeling as though you haven't rested, your diet could be a factor. Feeling sluggish or fatigued is a common byproduct of the low-grade inflammation associated with food intolerances.

4. Skin Flare-ups and Joint Pain

The effects of gluten are not always confined to the gut. For some, intolerance manifests as skin problems, such as unexplained rashes or eczema. Others may experience unexplained joint pain or "stiffness" that seems to fluctuate depending on what they have eaten over the previous few days.

The Smartblood Method: Step 1 – Consult Your GP

We cannot emphasise this enough: testing is not your first resort. If you suspect gluten is causing you grief, your very first port of call should be your NHS GP.

Why is this so important? Because if you have coeliac disease, you need a clinical diagnosis to access appropriate long-term care, including bone density monitoring and nutritional support. If you simply stop eating gluten before seeing a doctor, the tests for coeliac disease (which look for specific antibodies and sometimes require a biopsy) may come back as a "false negative" because the trigger has been removed from your system.

Your GP will help you rule out:

  • Coeliac Disease: Through a blood test (while you are still eating gluten).
  • Inflammatory Bowel Disease (IBD): Such as Crohn’s or Ulcerative Colitis.
  • Nutrient Deficiencies: Such as iron-deficiency anaemia or Vitamin B12 deficiency.
  • Thyroid Issues: Which can often mimic the fatigue and brain fog associated with intolerances.

Only once these medical conditions have been ruled out should you move on to the next phase of the Smartblood Method.

The Smartblood Method: Step 2 – The Elimination Approach

If your GP has given you the "all-clear" but your symptoms persist, it is time to become a health detective. The most reliable way to identify a food trigger is through a structured elimination diet. This involves removing suspected "problem foods" for a set period and then systematically reintroducing them to see how your body reacts.

Using a Symptom Diary

We recommend starting with our free food elimination diet chart and symptom tracker. For at least two weeks, record everything you eat and drink, along with any symptoms that occur. Be diligent. Note the time of the meal and the time the symptom started.

Consider this scenario: You have a sandwich for lunch on Monday. You feel fine all afternoon, but on Tuesday morning, you wake up with a headache and a bloated stomach. Without a diary, you might blame your Tuesday breakfast. With a diary, you might see a pattern where gluten and wheat consumption on one day consistently leads to symptoms the next.

The Challenge of Modern Eating

The difficulty with a solo elimination diet is that gluten is hidden everywhere. It’s in soy sauce, salad dressings, some sausages, and even some brands of chocolate. It can also be hard to tell if it’s the gluten itself or another component of the food, such as yeast or a high-FODMAP carbohydrate. This is where many people get stuck, feeling better but not knowing exactly why.

The Smartblood Method: Step 3 – Targeted IgG Testing

If you have tried an elimination diet and are still "stuck," or if you find the process of guessing too overwhelming, this is where the Smartblood Food Intolerance Test serves as a valuable tool.

What is IgG Testing?

Our test looks for food-specific IgG (Immunoglobulin G) antibodies. Think of IgG as the "memory" of your immune system. While IgE antibodies cause that immediate "emergency" reaction, IgG antibodies are often associated with more gradual, inflammatory responses.

We use a sophisticated laboratory technique called ELISA (Enzyme-Linked Immunosorbent Assay). In simple terms, we take your blood sample and see how it reacts to 282 different food and drink ingredients. If your blood produces a high level of IgG in response to a specific food, it suggests your body is mounting a reaction to it.

Framing the Results Responsibly

It is important to acknowledge that IgG testing is a subject of debate within the wider medical community. Some professionals view IgG purely as a marker of exposure—essentially saying your body "recognises" the food. However, at Smartblood, we view these results not as a final medical diagnosis, but as a biological "snapshot" that can guide a much more targeted and effective elimination plan.

Instead of guessing and cutting out entire food groups (which can lead to nutritional deficiencies), our scientific studies and internal data suggest that using a test to identify "high-reactivity" foods can significantly shorten the path to feeling better. Our results use a 0–5 scale, providing clarity on which foods are causing the most significant reaction.

Deciphering Your Results: Is It Just Gluten?

When you receive your results—typically within three working days after our lab receives your sample—you might find that gluten is only part of the story.

For example, many people who believe they are gluten intolerant actually have a high reactivity to dairy and eggs or perhaps even certain fruits and vegetables. If you only cut out gluten but continue to eat a "trigger" food like cow's milk or tomatoes, your symptoms may not fully resolve. This is the "Smartblood" difference: we help you understand your body’s unique landscape.

"A snapshot of your immune system’s reaction to 282 foods provides a level of clarity that months of guesswork often cannot match."

Once you have your report, you can begin a much more focused elimination phase. We provide guidance on how to temporarily remove high-reactivity foods and, crucially, how to reintroduce them later to test your tolerance levels. This ensures you don't stay on a restricted diet for longer than necessary.

Practical Steps for Living with Gluten Intolerance

If you have determined that gluten is indeed a trigger for you, the next step is managing your diet without feeling deprived. Living in the UK, we are fortunate that food labelling laws are quite strict.

Reading Labels

Always look for the bolded ingredients on packaging. By law, cereals containing gluten (wheat, rye, barley, oats) must be highlighted in the ingredients list. However, be wary of "cross-contamination." If a product is "made in a factory that handles wheat," it might be fine for someone with an intolerance, but dangerous for someone with coeliac disease.

Hidden Sources of Gluten

  • Sauces: Many gravies and ketchups use wheat flour as a thickener.
  • Alcohol: Beer, lager, and stout are usually made from barley. Opt for cider, wine, or specifically labelled gluten-free beers instead. Check our guide on drinks and intolerances for more.
  • Processed Meats: Some sausages and burgers use breadcrumbs as fillers.
  • Vitamins and Supplements: Some supplements use wheat-based binders.

Focus on Naturally Gluten-Free Foods

Instead of relying solely on expensive "free-from" processed substitutes, build your diet around naturally gluten-free staples:

  • Potatoes, sweet potatoes, and rice.
  • Quinoa, buckwheat, and millet.
  • Fresh meat and fish.
  • All fresh fruits and vegetables.
  • Pulses like lentils, chickpeas, and beans.

Why Choose Smartblood?

Smartblood was founded by experts who wanted to make food intolerance information accessible and high-trust. We aren't here to sell you a "quick fix" or make grand claims. We are here to provide a professional service that complements the work of your GP.

Our Food Intolerance Test is a simple home finger-prick kit. It is designed to be easy to use, and our results are delivered clearly via email, grouped by food category. We want to empower you to have better-informed conversations with your doctor or a nutritionist.

We believe that by understanding the science of IgG testing, you can take control of your health. Whether you are looking to optimise your fitness or simply stop the daily cycle of bloating and fatigue, we provide the data you need to make changes that stick.

Summary: Your Path to Clarity

Determining if you have a gluten intolerance is a journey, not a single event. To summarise the most effective route:

  1. Rule out the "Big Stuff" first: Visit your GP to ensure you don't have coeliac disease or an underlying digestive illness.
  2. Track and Trace: Use a symptom diary and our free elimination chart to see if you can spot obvious patterns over a two-week period.
  3. Use Data to Refine: If you are still struggling, consider an IgG blood test to identify specific reactivities across 282 different foods and drinks.
  4. Actionable Elimination: Use your test results to conduct a targeted 4-6 week elimination, followed by a careful reintroduction phase.

You don't have to accept bloating and brain fog as your "normal." By following a clinically responsible, phased approach, you can determine exactly what your body needs to thrive.

If you're ready to take the next step and remove the guesswork from your diet, the Smartblood Food Intolerance Test is available for £179.00. We frequently offer support to our community; you may find that the code ACTION provides a 25% discount if available on our site today.

For any questions about the process or how the test works, please visit our FAQ page or contact our team directly.

FAQ

Can I take a food intolerance test if I am already on a gluten-free diet? For the most accurate IgG results, it is generally recommended that you have been consuming the food in question regularly for at least four to six weeks. If you have already completely eliminated gluten, your IgG levels for that specific protein may have dropped, which could lead to a lower reactivity result on the test.

Is a food intolerance the same as coeliac disease? No. Coeliac disease is a serious autoimmune condition where gluten causes the body to attack its own small intestine. A food intolerance (or sensitivity) is usually a delayed reaction that causes discomfort and inflammation but does not cause the same type of permanent intestinal damage. Smartblood tests do not diagnose coeliac disease.

How long does it take to see results after cutting out gluten? This varies by individual. Some people notice a reduction in bloating within a few days, while for others, "brain fog" or skin issues may take several weeks to clear as the body’s inflammatory response calms down. This is why we recommend a minimum 4-week elimination period.

Does this test cover other grains besides wheat? Yes. Our comprehensive analysis covers 282 foods and drinks, including various grains like barley, rye, spelt, and oats, as well as gluten-free alternatives like quinoa and buckwheat. This helps you determine if your issue is specifically with gluten or perhaps another component of a certain grain.

Medical Disclaimer

The information provided in this article is for educational and informational purposes only and does not constitute medical advice. You should always consult your GP or a qualified healthcare professional before making significant changes to your diet, especially if you have underlying health conditions. The Smartblood Food Intolerance Test is an IgG-based analysis intended to help guide a structured elimination and reintroduction diet; it is not a diagnostic tool for food allergies (IgE), coeliac disease, or any other medical condition. If you experience symptoms of a severe allergic reaction, such as swelling of the throat or difficulty breathing, seek emergency medical care immediately by calling 999.